Title : Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages.

Pub. Date : 2004 May 7

PMID : 15081398






1 Functional Relationships(s)
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1 BP-treatment was found to dramatically alter their functional capacities and to trigger a caspase- and mitochondrion-related apoptosis, associated with down-regulation of the survival factors c-FLIP(L) and Bcl-X(L) and up-regulation of the pro-apoptotic factor p53. Benzo(a)pyrene tumor protein p53 Homo sapiens