Title : Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.

Pub. Date : 2004 Apr 1

PMID : 15073105






1 Functional Relationships(s)
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1 CONCLUSIONS: These data demonstrate that hypoxia can induce resistance of pancreatic cancer cells to gemcitabine mainly through the PI3K/Akt/NF-kappa B pathways and partially through the MAPK(Erk) signaling pathway. gemcitabine mitogen-activated protein kinase 1 Homo sapiens