Title : Herbal modulation of P-glycoprotein.

Pub. Date : 2004 Feb

PMID : 15072439






3 Functional Relationships(s)
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1 Curcumin, ginsenosides, piperine, some catechins from green tea, and silymarin from milk thistle were found to be inhibitors of Pgp, while some catechins from green tea increased Pgp-mediated drug transport by heterotropic allosteric mechanism, and St. John"s wort induced the intestinal expression of Pgp in vitro and in vivo. Curcumin ATP binding cassette subfamily B member 1 Homo sapiens
2 Curcumin, ginsenosides, piperine, some catechins from green tea, and silymarin from milk thistle were found to be inhibitors of Pgp, while some catechins from green tea increased Pgp-mediated drug transport by heterotropic allosteric mechanism, and St. John"s wort induced the intestinal expression of Pgp in vitro and in vivo. Curcumin ATP binding cassette subfamily B member 1 Homo sapiens
3 Curcumin, ginsenosides, piperine, some catechins from green tea, and silymarin from milk thistle were found to be inhibitors of Pgp, while some catechins from green tea increased Pgp-mediated drug transport by heterotropic allosteric mechanism, and St. John"s wort induced the intestinal expression of Pgp in vitro and in vivo. Curcumin ATP binding cassette subfamily B member 1 Homo sapiens