Pub. Date : 2004 Apr 13
PMID : 15064408
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxygen and the copper chaperone CCS regulate posttranslational activation of Cu,Zn superoxide dismutase. | Oxygen | superoxide dismutase 1 | Homo sapiens |
| 2 | Data presented here are consistent with a previously uncharacterized function for CCS in the SOD1 pathway, namely mediating enzyme activation in response to increases in oxygen tension. | Oxygen | superoxide dismutase 1 | Homo sapiens |
| 3 | This CCS function provides oxidant-responsive posttranslational regulation of SOD1 activity and may be relevant to a wide array of physiological stresses that involve a sudden elevation of oxygen availability. | Oxygen | superoxide dismutase 1 | Homo sapiens |