Title : Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

Pub. Date : 2004 May

PMID : 15060738






1 Functional Relationships(s)
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1 RESULTS: Ortataxel effectively modulated drug retention and cytotoxicity in cell lines overexpressing MRP-1 and BCRP(R482), in addition to Pgp. IDN 5109 ATP binding cassette subfamily C member 1 Homo sapiens