Title : Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

Pub. Date : 2004 May

PMID : 15060738






2 Functional Relationships(s)
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Protein Name
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1 PURPOSE: The taxanes paclitaxel and docetaxel are substrates for P-glycoprotein (Pgp), an ATP-binding cassette (ABC) transport protein associated with multidrug resistance (MDR). Taxoids ATP binding cassette subfamily B member 1 Homo sapiens
2 PURPOSE: The taxanes paclitaxel and docetaxel are substrates for P-glycoprotein (Pgp), an ATP-binding cassette (ABC) transport protein associated with multidrug resistance (MDR). Taxoids ATP binding cassette subfamily B member 1 Homo sapiens