Title : p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis.

Pub. Date : 2004 Apr 1

PMID : 15059885






1 Functional Relationships(s)
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1 Microarray expression analysis of doxorubicin exposed, related human lymphoblasts, p53 wild-type (WT) Tk6, and p53 mutant WTK1 identified the p53-dependent up-regulation of manganese superoxide dismutase (MnSOD) and glutathione peroxidase 1 (GPx). Doxorubicin superoxide dismutase 2 Homo sapiens