Title : A c-Jun NH2-terminal kinase inhibitor SP600125 (anthra[1,9-cd]pyrazole-6 (2H)-one) blocks activation of pancreatic stellate cells.

Pub. Date : 2004 Aug

PMID : 15056726






1 Functional Relationships(s)
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1 SP600125 inhibited interleukin-1beta-induced JNK activity and activator protein-1 activation, but it did not affect the activation of extracellular-regulated kinase, p38 mitogen-activated protein kinase, and nuclear factor-kappaB. pyrazolanthrone interleukin 1 beta Rattus norvegicus