Title : Conformational changes in monoamine oxidase A in response to ligand binding or reduction.

Pub. Date : 2004 Apr 7

PMID : 15056494






1 Functional Relationships(s)
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Protein Name
Organism
1 CD spectra of MAO A indicate that a small inhibitor such d-amphetamine perturbs the aromatic residues very little, but binding of the larger pirlindole (2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-j,k]carbazole hydrochloride) causes spectral changes consistent with the alteration of the environment of tyrosine and tryptophan residues in particular. Tyrosine monoamine oxidase A Homo sapiens