Title : Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway.

Pub. Date : 2004 Apr 15

PMID : 15051507






1 Functional Relationships(s)
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1 Further confirmation of cdk5 involvement in this process was based on the findings that inhibition of the kinase activity with butyrolactone-I prevents the appearance of tau of Alzheimer type in IL-6-treated neurons. 4-Butyrolactone cyclin dependent kinase 5 Homo sapiens