Title : NIH3T3 transfectant containing human K-ras oncogene shows enhanced metastatic activity after in vivo tumor growth or co-culture with fibroblasts.

Pub. Date : 1992 Sep

PMID : 1505125






1 Functional Relationships(s)
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1 After removal of fibroblasts by exposure to G-418, the tumor cells exhibited increased metastatic ability and human K-ras oncogene mRNA, suggesting an intimate interaction between H-3 cells and fibroblasts influencing the function of transfected human K-ras oncogene. antibiotic G 418 KRAS proto-oncogene, GTPase Homo sapiens