Title : Doxycycline and protein folding agents rescue the abnormal phenotype of familial CJD H187R in a cell model.

Pub. Date : 2004 Apr 7

PMID : 15046864






1 Functional Relationships(s)
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1 Interestingly, exposure of PrP(187R-GFP) cells to low temperature (28 degrees C) or to the chemical chaperones dimethyl sulphoxide (DMSO) and glycerol also reversed the mutant phenotype. Glycerol prion protein Homo sapiens