Title : UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver.

Pub. Date : 2004 Aug

PMID : 15044558






4 Functional Relationships(s)
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1 UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver. Oxazepam UDP glucuronosyltransferase family 2 member B15 Homo sapiens
2 UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver. Oxazepam UDP glucuronosyltransferase family 2 member B15 Homo sapiens
3 We have previously shown that S-oxazepam glucuronide, the major oxazepam metabolite, is selectively formed by UDP-glucuronosyltransferase (UGT) 2B15, whereas the minor R-oxazepam glucuronide is produced by multiple UGTs other than UGT2B15. Oxazepam UDP glucuronosyltransferase family 2 member B15 Homo sapiens
4 We have previously shown that S-oxazepam glucuronide, the major oxazepam metabolite, is selectively formed by UDP-glucuronosyltransferase (UGT) 2B15, whereas the minor R-oxazepam glucuronide is produced by multiple UGTs other than UGT2B15. Oxazepam UDP glucuronosyltransferase family 2 member B15 Homo sapiens