Pub. Date : 2004 Apr 15
PMID : 15041471
15 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1). | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 2 | In addition, MRP1/ABCC1 mediates cellular export of natural folates, such as folic acid and l-leucovorin. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 3 | In addition, MRP1/ABCC1 mediates cellular export of natural folates, such as folic acid and l-leucovorin. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 4 | In addition, MRP1/ABCC1 mediates cellular export of natural folates, such as folic acid and l-leucovorin. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 5 | In addition, MRP1/ABCC1 mediates cellular export of natural folates, such as folic acid and l-leucovorin. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 6 | In this study we determined whether cellular folate status affected the functional activity of MRP1/ABCC1 mediated efflux of an established substrate, the anthracycline daunorubicin (DNR). | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 7 | In this study we determined whether cellular folate status affected the functional activity of MRP1/ABCC1 mediated efflux of an established substrate, the anthracycline daunorubicin (DNR). | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 8 | Both types of these moderate- and high-MRP1/ABCC1 expressing cells displayed efflux of DNR when maintained in standard culture media (2.3microM folic acid). | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 9 | Both types of these moderate- and high-MRP1/ABCC1 expressing cells displayed efflux of DNR when maintained in standard culture media (2.3microM folic acid). | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 10 | When 2008/MRP1 cells were challenged for 2 days in folate-free medium, total cellular DNR efflux was decreased to 43% of the initial efflux rate under folate-rich conditions. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 11 | When 2008/MRP1 cells were challenged for 2 days in folate-free medium, total cellular DNR efflux was decreased to 43% of the initial efflux rate under folate-rich conditions. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 12 | In conclusion, this study demonstrates that the cellular folate status can influence the transport activity of MRP1/ABCC1. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 13 | In conclusion, this study demonstrates that the cellular folate status can influence the transport activity of MRP1/ABCC1. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 14 | These results have potentially important implications in the understanding of the (patho-)physiological roles of MRP1/ABCC1, and possibly other ABC transporter proteins in cellular folate homeostasis and drug resistance. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 15 | These results have potentially important implications in the understanding of the (patho-)physiological roles of MRP1/ABCC1, and possibly other ABC transporter proteins in cellular folate homeostasis and drug resistance. | Folic Acid | ATP binding cassette subfamily C member 1 | Homo sapiens |