Pub. Date : 2004 May 28
PMID : 15039448
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Glutathione propagates oxidative stress triggered by myeloperoxidase in HL-60 cells. | Glutathione | myeloperoxidase | Homo sapiens |
2 | Horseradish peroxidase-, myeloperoxidase-, and cyclooxygenasecatalyzed oxidation of phenol in the presence of H2O2 and GSH caused the generation of phenoxyl radicals and GS* radicals, of which only the latter reacted with Ac-Tempo. | Glutathione | myeloperoxidase | Homo sapiens |
3 | Thus, GSH, commonly viewed as a universal free radical scavenger and major intracellular antioxidant, acts as a pro-oxidant during myeloperoxidase-catalyzed metabolism of phenol in HL-60 cells. | Glutathione | myeloperoxidase | Homo sapiens |