Pub. Date : 2004 Feb 1
PMID : 15037197
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep. | 4-nitrobenzylthioinosine | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
| 2 | hENT1 and hENT2 differ in their affinity for nucleoside substrates and in their sensitivity to inhibitors, such as nitrobenzylthioinosine (NBMPR). | 4-nitrobenzylthioinosine | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
| 3 | hENT1 and hENT2 differ in their affinity for nucleoside substrates and in their sensitivity to inhibitors, such as nitrobenzylthioinosine (NBMPR). | 4-nitrobenzylthioinosine | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
| 4 | Since NBMPR competitively inhibits nucleoside transporter activity, we hypothesized that G154 may also play a role in the transport of natural nucleosides and in the inhibition by other hENT1 inhibitors, dipyridamole (DP), and dilazep (DZ). | 4-nitrobenzylthioinosine | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |