Title : ADAM is an effective tool for in vivo study of serotonergic function: validation in rat models.

Pub. Date : 2004 May

PMID : 15034919






1 Functional Relationships(s)
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1 The higher in vivo binding of [125I]ADAM in pCPA-treated rats than in controls was mainly due to an increase in specific binding to the SERT, as demonstrated by greatly reduced binding in the presence of a saturating dose of paroxetine. Paroxetine ADAM metallopeptidase domain 7 Rattus norvegicus