Pub. Date : 2004 Apr 9
PMID : 15033457
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cholesterol modulates P-glycoprotein activity in human peripheral blood mononuclear cells. | Cholesterol | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | P-gp is known to be located in membrane microdomains, whose structure and function are susceptible to cholesterol alterations. | Cholesterol | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | This study evaluated the effect of cholesterol alteration in human PBMCs on P-gp activity. | Cholesterol | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | These data demonstrate that elevated cellular cholesterol levels can markedly increase P-gp activity in human PBMCs. | Cholesterol | ATP binding cassette subfamily B member 1 | Homo sapiens |