Pub. Date : 2003 Dec
PMID : 15028566
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We tested whether agmatine affects astroglial and macrophage (RAW 264.7 cell line) nitric oxide synthase-2 (NOS-2) expression. | Agmatine | nitric oxide synthase 2, inducible | Mus musculus |
| 2 | We tested whether agmatine affects astroglial and macrophage (RAW 264.7 cell line) nitric oxide synthase-2 (NOS-2) expression. | Agmatine | nitric oxide synthase 2, inducible | Mus musculus |
| 3 | NOS-2 was induced in these cells by incubation with lipopolysaccharide (LPS) plus three cytokines for astrocytes and LPS alone for RAW 264.7 cells in the presence and absence of varying concentrations of agmatine. | Agmatine | nitric oxide synthase 2, inducible | Mus musculus |
| 4 | Agmatine decreased the expression of NOS-2 activity and NOS-2 protein as determined by immunoblot analysis. | Agmatine | nitric oxide synthase 2, inducible | Mus musculus |
| 5 | Agmatine decreased the expression of NOS-2 activity and NOS-2 protein as determined by immunoblot analysis. | Agmatine | nitric oxide synthase 2, inducible | Mus musculus |
| 6 | These results show that agmatine inhibits the production of nitric oxide by decreasing the activity of NOS-2 in macrophages and astroglial cells by decreasing the levels of NOS-2 protein. | Agmatine | nitric oxide synthase 2, inducible | Mus musculus |
| 7 | These results show that agmatine inhibits the production of nitric oxide by decreasing the activity of NOS-2 in macrophages and astroglial cells by decreasing the levels of NOS-2 protein. | Agmatine | nitric oxide synthase 2, inducible | Mus musculus |