Title : Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells.

Pub. Date : 2004 Jul 1

PMID : 15027896






2 Functional Relationships(s)
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1 These results demonstrate that Ang II stimulates ERK1/ERK2 by AA and Nox4-derived reactive oxygen species, suggesting that these molecules act as downstream signal transducers of Ang II in the signalling pathway linking the Ang II receptor AT1 to ERK1/ERK2 activation. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens
2 These results demonstrate that Ang II stimulates ERK1/ERK2 by AA and Nox4-derived reactive oxygen species, suggesting that these molecules act as downstream signal transducers of Ang II in the signalling pathway linking the Ang II receptor AT1 to ERK1/ERK2 activation. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens