Pub. Date : 2004 Mar 25
PMID : 15027867
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Rasagiline has the highest specificity for MAO B, as demonstrated by a 100-fold higher inhibition potency (k(inact)/K(i)) compared to MAO A, with the remaining compounds exhibiting lower isozyme specificities. | rasagiline | monoamine oxidase B | Homo sapiens |
2 | MAO B and MAO A are more selective for the R-enantiomer (rasagiline) compared to the S-enantiomer (S-PAI) by 2500-fold and 17-fold, respectively. | rasagiline | monoamine oxidase B | Homo sapiens |
3 | Differences in UV/vis and CD spectral data of the complexes of the studied compounds with both MAO A and MAO B are interpreted in light of crystallographic data of complexes of MAO B with rasagiline and its analogues (Binda, C.; et al. | rasagiline | monoamine oxidase B | Homo sapiens |
4 | Differences in UV/vis and CD spectral data of the complexes of the studied compounds with both MAO A and MAO B are interpreted in light of crystallographic data of complexes of MAO B with rasagiline and its analogues (Binda, C.; et al. | rasagiline | monoamine oxidase B | Homo sapiens |