Pub. Date : 2004 Mar 15
PMID : 15020199
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In search for novel markers of skin tumor promotion, we found that TPA application to mouse skin resulted, as an early event, in an increased expression of phosphatidyinositol 3-kinase (PI3K), phosphorylation of Akt at threonine308 and activation of nuclear factor kappa B (NF-kappaB). | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Topical application of oleandrin before TPA application to mouse skin resulted in significant reduction in TPA-induced expression of PI3K and phosphorylation of Akt, and inhibition of NF-kappaB activation. | Tetradecanoylphorbol Acetate | thymoma viral proto-oncogene 1 | Mus musculus |