Title : 3-O-deacylation of lipid A by PagL, a PhoP/PhoQ-regulated deacylase of Salmonella typhimurium, modulates signaling through Toll-like receptor 4.

Pub. Date : 2004 May 7

PMID : 15014080






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A variety of different data indicate that the acylation state of lipid A can alter TLR4-mediated responses. Lipid A toll like receptor 4 Homo sapiens
2 We now demonstrate that 3-O-deacylation and palmitoylation of lipid A decreases its ability to induce TLR4-mediated signaling. Lipid A toll like receptor 4 Homo sapiens