Title : Cys residues of the hepatitis B virus capsid protein are not essential for the assembly of viral core particles but can influence their stability.

Pub. Date : 1992 Sep

PMID : 1501280






2 Functional Relationships(s)
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1 Fractionation of radiolabeled oocyte extracts on 10 to 60% sucrose gradients revealed that Cys-minus core proteins resolved into the nonparticulate and capsid forms seen for wild-type p21.5. Cysteine H3 histone pseudogene 16 Homo sapiens
2 However, Cys residues stabilize isolated p21.5 structures, as evidenced by the marked reduction in stability of Cys-minus dimers and capsids (i) in nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis and (ii) upon protease digestion. Cysteine H3 histone pseudogene 16 Homo sapiens