Title : Antipsoriatic drug anthralin induces EGF receptor phosphorylation in keratinocytes: requirement for H(2)O(2) generation.

Pub. Date : 2004 Feb

PMID : 15009100






1 Functional Relationships(s)
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1 Our data identify anthralin-induced reactive oxygen species and, more specifically, H(2)O(2) as an important upstream mediator required for ligand-independent epidermal growth factor receptor phosphorylation and downstream signaling. Hydrogen Peroxide epidermal growth factor receptor Homo sapiens