Title : Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration.

Pub. Date : 2004 Mar 4

PMID : 15003169






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 SBMA is caused by polyglutamine repeat expansions in the androgen receptor (AR). polyglutamine androgen receptor Mus musculus
2 SBMA is caused by polyglutamine repeat expansions in the androgen receptor (AR). polyglutamine androgen receptor Mus musculus
3 We then tested the hypothesis that polyglutamine-expanded AR interferes with CREB binding protein (CBP)-mediated transcription of vascular endothelial growth factor (VEGF) and observed altered CBP-AR binding and VEGF reduction in AR100 mice. polyglutamine androgen receptor Mus musculus