Title : Influence of compartmental localization on the function of yeast NADP+-specific isocitrate dehydrogenases.

Pub. Date : 2004 Mar 15

PMID : 15001388






1 Functional Relationships(s)
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1 Three differentially compartmentalized isozymes of isocitrate dehydrogenase (mitochondrial IDP1, cytosolic IDP2, and peroxisomal IDP3) in the yeast Saccharomyces cerevisiae catalyze the NADP(+)-dependent oxidative decarboxylation of isocitrate to form alpha-ketoglutarate. isocitric acid isocitrate dehydrogenase (NADP(+)) IDP1 Saccharomyces cerevisiae S288C