Title : Effect of RU 38486 on TNF production and toxicity.

Pub. Date : 1992 Aug 17

PMID : 1499722






3 Functional Relationships(s)
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Protein Name
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1 Glucocorticoid steroids provide considerable protection against the systemic toxicity of tumor necrosis factor-alpha (TNF-alpha, cachexin). Steroids tumor necrosis factor Homo sapiens
2 Glucocorticoid steroids provide considerable protection against the systemic toxicity of tumor necrosis factor-alpha (TNF-alpha, cachexin). Steroids tumor necrosis factor Homo sapiens
3 In animal experiments RU 38486 (mifepristone), a steroid antagonist, increased the synthesis of TNF and sensitized the animals to the cytotoxic action of TNF. Steroids tumor necrosis factor Homo sapiens