Title : Modest catalysis of the decarboxylation of orotate by hydrogen bonding: a theoretical model for orotidine- 5' -monophosphate decarboxylase.

Pub. Date : 2004 Apr

PMID : 14990306






1 Functional Relationships(s)
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1 As a model for interactions present in the active site of orotidine-5"-monophosphate decarboxylase (ODCase), the effect of hydrogen bonds to the carbonyl groups (O-2 and O-4) of orotic acid and its decarboxylation product was probed with ab initio calculations. Hydrogen immunoglobulin kappa variable 1D-39 Homo sapiens