Title : Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate-stimulated MAPK activation, Cox-2 and IL-8 expression.

Pub. Date : 2004 Feb 27

PMID : 14984736






2 Functional Relationships(s)
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1 When either isoform of PLD was stably expressed in HEK-293 cells, we observed an increased PLD activity in a cell-free system and a 12-O-tetradecanoyl-13-phorbol acetate (TPA)-stimulated increase in PLD activity in intact cells. Tetradecanoylphorbol Acetate glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 This system was then used to elucidate the effects of PLD activity on TPA-stimulated signaling pathways. Tetradecanoylphorbol Acetate glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens