Title : RAD6B overexpression confers chemoresistance: RAD6 expression during cell cycle and its redistribution to chromatin during DNA damage-induced response.

Pub. Date : 2004 Apr 15

PMID : 14981545






1 Functional Relationships(s)
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1 The increase in RAD6 protein expression observed in ADR-treated cells is dependent upon transcription and de novo protein synthesis, as addition of actinomycin D and cycloheximide eliminated the induction effects. Cycloheximide E2 ubiquitin-conjugating protein RAD6 Saccharomyces cerevisiae S288C