Title : Identification of novel alternative splice variants of human constitutive androstane receptor and characterization of their expression in the liver.

Pub. Date : 2004 Mar

PMID : 14978227






2 Functional Relationships(s)
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1 In the reporter gene assays employing the phenobarbital-responsible enhancer module (PBREM) from CYP2B6 and UGT1A1 genes, the splice variants, except for SV1, were inactive, whereas SV1 transactivated the CYP2B6 PBREM but not the UGT1A1 PBREM reporter. Phenobarbital UDP glucuronosyltransferase family 1 member A1 Homo sapiens
2 In the reporter gene assays employing the phenobarbital-responsible enhancer module (PBREM) from CYP2B6 and UGT1A1 genes, the splice variants, except for SV1, were inactive, whereas SV1 transactivated the CYP2B6 PBREM but not the UGT1A1 PBREM reporter. Phenobarbital UDP glucuronosyltransferase family 1 member A1 Homo sapiens