Title : Anabolic potential of fibroblasts from chronically inflamed gingivae grown in a hyperglycemic culture medium in the presence or absence of insulin and nicotine.

Pub. Date : 2003 Dec

PMID : 14974818






2 Functional Relationships(s)
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1 (4) The independent inhibitory effects of nicotine and glucose on metabolic yields of DHT were marginally more pronounced in combination but significantly overcome in the presence of insulin. Nicotine insulin Homo sapiens
2 CONCLUSION: Human gingival fibroblasts obtained from chronically inflamed tissue of nondiabetic patients demonstrated that the inhibitory effects of glucose and nicotine on androgen metabolism can be overcome by insulin, in varying degrees. Nicotine insulin Homo sapiens