Title : Cardioprotection with phosphodiesterase-5 inhibition--a novel preconditioning strategy.

Pub. Date : 2004 Feb

PMID : 14871543






3 Functional Relationships(s)
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1 Phosphodiesterase type-5 (PDE-5) inhibitors including sildenafil, vardenafil and tadalafil are a new class of vasoactive drugs that have been developed for treatment of erectile dysfunction in patients. Sildenafil Citrate phosphodiesterase 5A Homo sapiens
2 Phosphodiesterase type-5 (PDE-5) inhibitors including sildenafil, vardenafil and tadalafil are a new class of vasoactive drugs that have been developed for treatment of erectile dysfunction in patients. Sildenafil Citrate phosphodiesterase 5A Homo sapiens
3 Future demonstration of the cardioprotective effect in patients with the relatively safe and effective FDA-approved PDE-5 inhibitors, such as sildenafil, could have an enormous impact on bringing the long-studied phenomena of ischemic and pharmacologic preconditioning to the clinical forefront. Sildenafil Citrate phosphodiesterase 5A Homo sapiens