Title : p53 immunostaining in the distinction between benign and malignant mesothelial proliferations using formalin-fixed paraffin sections.

Pub. Date : 1992 Dec

PMID : 1484319






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 p53 immunostaining in the distinction between benign and malignant mesothelial proliferations using formalin-fixed paraffin sections. Paraffin tumor protein p53 Homo sapiens
2 The object of this study was to examine the frequency of immunohistochemically detectable p53 overexpression in routinely processed, paraffin-embedded tissue from pleural mesotheliomas and from pleura showing reactive mesothelial hyperplasia, using a polyclonal antibody to formalin-resistant p53 epitopes, and to consider the diagnostic utility of this antibody in the distinction between mesothelioma and reactive mesothelium in pleural biopsy specimens. Paraffin tumor protein p53 Homo sapiens
3 In conclusion, this study suggests that p53 immunostaining can help to distinguish epithelial or biphasic mesothelioma from reactive mesothelial hyperplasia in formalin-fixed, paraffin-embedded pleural biopsy specimens. Paraffin tumor protein p53 Homo sapiens