Pub. Date : 2003 May
PMID : 14768176
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased glucose metabolism through the hexosamine biosynthesis pathway has been shown to mediate many of adverse effects i.e. desensitisation of glucose transport in tissues, an inhibition of glycolysis and glycogen synthesis in skeletal muscles, an impairment of insulin secretion in pancreatic islet cells, arteriosclerosis and nephropathy by stimulation of growth factor TGF-alpha and TGF-beta 1 promoters expression. | Hexosamines | transforming growth factor beta 1 | Homo sapiens |