Title : Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.

Pub. Date : 2004 Jan 15

PMID : 14760102






2 Functional Relationships(s)
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Protein Name
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1 Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy. vandetanib vascular endothelial growth factor A Mus musculus
2 ZD6474 is a small molecule VEGF flk-1/KDR (VEGFR-2) tyrosine kinase inhibitor that also demonstrates inhibitory activity against EGFR tyrosine kinase. vandetanib vascular endothelial growth factor A Mus musculus