Title : Differential enantioselectivity and product-dependent activation and inhibition in metabolism of verapamil by human CYP3As.

Pub. Date : 2004 Feb

PMID : 14744940






1 Functional Relationships(s)
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1 In vitro studies of enantioselective metabolism of R-(+)- and S-(-)verapamil (VER) were conducted using human cDNA-expressed CYP3A isoforms, CYP3A4, CYP3A5, and CYP3A7. Verapamil cytochrome P450 family 3 subfamily A member 4 Homo sapiens