Title : Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells.

Pub. Date : 2004 Apr 2

PMID : 14742435






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Our results suggest that COX-2/PGE(2) may exert pro-oncogenic effects through synergistic induction of receptor tyrosine kinase-dependent signaling pathway, thus, provide a novel mechanism for the combinatorial treatment of colonic neoplasms targeting both COX-2/PGE(2) and the EGFR system that has demonstrated remarkable advantages. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Our results suggest that COX-2/PGE(2) may exert pro-oncogenic effects through synergistic induction of receptor tyrosine kinase-dependent signaling pathway, thus, provide a novel mechanism for the combinatorial treatment of colonic neoplasms targeting both COX-2/PGE(2) and the EGFR system that has demonstrated remarkable advantages. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens
3 Our results suggest that COX-2/PGE(2) may exert pro-oncogenic effects through synergistic induction of receptor tyrosine kinase-dependent signaling pathway, thus, provide a novel mechanism for the combinatorial treatment of colonic neoplasms targeting both COX-2/PGE(2) and the EGFR system that has demonstrated remarkable advantages. Prostaglandins E mitochondrially encoded cytochrome c oxidase II Homo sapiens