Title : Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kappaB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells.

Pub. Date : 2004 Feb 13

PMID : 14741691






1 Functional Relationships(s)
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1 iNOS expression and NO secretion in response to LPS were suppressed by Ca(2+) antagonists (TMB-8, BAPTA/AM, and nifedipine) and CN inhibitor (cyclosporin A). Cyclosporine nitric oxide synthase 2, inducible Mus musculus