Title : Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions.

Pub. Date : 2004 Apr 2

PMID : 14734554






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 hNTH1 and hNEIL1 but not hNEIL2 excised the two stereoisomers of thymine glycol (5R-Tg and 5S-Tg), but their isomer specificity was markedly different: the relative activity for 5R-Tg:5S-Tg was 13:1 for hNTH1 and 1.5:1 for hNEIL1. 5s-tg nth like DNA glycosylase 1 Homo sapiens
2 hNTH1 and hNEIL1 but not hNEIL2 excised the two stereoisomers of thymine glycol (5R-Tg and 5S-Tg), but their isomer specificity was markedly different: the relative activity for 5R-Tg:5S-Tg was 13:1 for hNTH1 and 1.5:1 for hNEIL1. 5s-tg nth like DNA glycosylase 1 Homo sapiens