Title : Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells.

Pub. Date : 2004 Jan 1

PMID : 14732213






2 Functional Relationships(s)
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1 RESULTS: Ang II-increased DNA synthesis was inhibited by AT(1) receptor antagonist (olmesartan) and ET(A) receptor antagonist (BQ485). olmesartan angiotensinogen Rattus norvegicus
2 Ang II-increased intracellular ROS levels were inhibited by olmesartan and antioxidants. olmesartan angiotensinogen Rattus norvegicus