Title : Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1.

Pub. Date : 2004 Jan

PMID : 14720319






1 Functional Relationships(s)
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1 Significantly, gene expression of CYP1A1 and 1B1 is induced by PAHs and polyhalogenated hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin through the arylhydrocarbon receptor. Hydrocarbons cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus