Title : Induction of leukotriene C4 synthase activity in differentiating human erythroleukemia cells.

Pub. Date : 1992 Dec 15

PMID : 1472015






2 Functional Relationships(s)
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1 The present report describes the induction of LTC4 synthase activity during differentiation of human erythroleukemia (HEL) cells by the protein kinase C stimulator 12-O-tetradecanoyl phorbol 13-acetate (TPA), ligands of the steroid-thyroid hormone receptor superfamily: all-trans-retinoic acid (RA) and 1 alpha, 25-dihydroxy-vitamin D3 and in addition dimethylsulfoxide (DMSO). Dimethyl Sulfoxide leukotriene C4 synthase Homo sapiens
2 The present report describes the induction of LTC4 synthase activity during differentiation of human erythroleukemia (HEL) cells by the protein kinase C stimulator 12-O-tetradecanoyl phorbol 13-acetate (TPA), ligands of the steroid-thyroid hormone receptor superfamily: all-trans-retinoic acid (RA) and 1 alpha, 25-dihydroxy-vitamin D3 and in addition dimethylsulfoxide (DMSO). Dimethyl Sulfoxide leukotriene C4 synthase Homo sapiens