Title : Catechol-O-methyltransferase polymorphism alters hypothalamic-pituitary-adrenal axis responses to naloxone: a preliminary report.

Pub. Date : 2004 Jan 1

PMID : 14706432






1 Functional Relationships(s)
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1 BACKGROUND: A common polymorphism in the catechol-O-methyltransferase gene involves a valine to methionine mutation that results in a threefold to fourfold decrease in enzyme activity. Methionine catechol-O-methyltransferase Homo sapiens