Title : (-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties.

Pub. Date : 2004 Jan

PMID : 14697898






1 Functional Relationships(s)
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1 (-)-Deprenyl in much lower concentrations needed to induce MAO-B inhibition (10(-9) to 10(-13) M) potently inhibits MPTP or serum withdrawal induced apoptosis in tissue cultures of neuro-ectodermal origin (PC12, M1, M2058). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine monoamine oxidase B Homo sapiens