Title : SAM68: a downstream target of angiotensin II signaling in vascular smooth muscle cells in genetic hypertension.

Pub. Date : 2004 May

PMID : 14693677






1 Functional Relationships(s)
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1 Inhibition of PI3K, using the selective inhibitor LY-294002, and downregulation of SAM68, by antisense oligonucleotides, significantly decreased ANG II-stimulated incorporation of [3H]leucine and [3H]thymidine in VSMCs, showing the functional significance of PI3K and SAM68. Leucine angiotensinogen Rattus norvegicus