Pub. Date : 2004 Jan
PMID : 14681721
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | hTERT-promoter-based tumor-specific expression of MCP-1 effectively sensitizes cervical cancer cells to a low dose of cisplatin. | Cisplatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | However, when combined with a suboptimal low dose of cisplatin, tumor formation was obviously reduced in clones transduced with MCP-1, but not in control clones. | Cisplatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | These findings suggest that MCP-1 expression sensitizes cervical cancer cells to an otherwise ineffective low dose of cisplatin, possibly by inducing the migration of macrophages to eradicate tumor cells. | Cisplatin | C-C motif chemokine ligand 2 | Homo sapiens |