Title : Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover.

Pub. Date : 2004 Mar 5

PMID : 14681225






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 By using the peptidylprolyl isomerase, Pin1, as a probe for proline-directed phosphorylation, we show that ERK1/2-dependent phosphorylation of Bim(EL) occurs at (S/T)P motifs. Proline peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens