Title : Pharmacological characteristics of Ro 115-1240, a selective alpha1A/1L-adrenoceptor partial agonist: a potential therapy for stress urinary incontinence.

Pub. Date : 2004 Jan

PMID : 14678390






1 Functional Relationships(s)
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1 The potency and intrinsic activity of amidephrine and Ro 115-1240 relative to noradrenaline were determined in native and cell-based assays using human recombinant alpha1-ARs; they acted as selective alpha1A/1L-AR full and partial agonists, respectively. Norepinephrine calcium voltage-gated channel subunit alpha1 A Homo sapiens